The emergence of a new air combat paradigm may have the same destabilizing effect that advances in naval architecture caused in the early 20th century. Advances in turbine propulsion, director fire control and armor made the naval power of Great Britain obsolescent at a stroke. Not only did this deprecate the vast legacy store of British warships, it rendered many of the traditional skills of seafaring valueless.
The real measure of an airforce, as has been pointed out by commenters on the Belmont Club, is not in the airplanes but in the airmen. If pilot skills are automated to a degree wherein relatively unskilled persons can become viable air fighters then the huge investment of the US military in traditional pilot skills will be lost. As with the Dreadnought era all world powers will essentially find themselves starting at zero.